Reef Rescuers is a coral reef restoration project funded by USAID (United States Agency for International Development), implemented by Nature Seychelles, a leading environmental NGO located in Seychelles, Indian Ocean. The project aims to restore Seychelles´coral reefs. The first phase generated a pool of 40,000 farmed coral colonies (fragments from healthy donor colonies, or corals of opportunity –corals detached with no chance of survival) reared in underwater nurseries to transplantable size. The second phase consisted of transplanting over 25,000 nursery-grown corals onto 5 255 sq mt of degraded reef. We observed a five-fold increase in fish species richness, a three-fold increase in fish density, and a two-fold increase in coral settlement and recruitment at the transplanted site. Our results support the application of large-scale, science-based coral reef restoration projects with long timescales to assist the recovery of damaged reefs.